It depends on the intent of the statement though
But yeah they most likely do think SpongeBob is cute and adorable and perhaps like Grass-Skirt-Chase said they may even have a crush on him...
And they're right
SpongeBob SquarePants is one of the most adorable cartoon characters NOT named "Mickey Mouse"!
Although, the Rugrats can give him a run for his money
Anyway, considering the different designs & outfits that SpongeBob, Mr. Krabs, and Squidward have worn over the years (especially the fancy tuxedos with bow-ties as seen in "Squilliam Returns") I can see why the women would be fawning all over them
Lol
I just watched the episode "Sun Bleached" on NickToons and when SpongeBob was covered in caramel topping to fake his tan, if there were any females around I am sure they would have wanted to eat him up!
Another instance where SpongeBob SquarePants was covered in a yummy substance was the episode "License to Milkshake" where he was covered head-to-toe in whipped cream