If they have a promotion with McDonald's and therefore a commercial I would be shocked at this point if they didn't use the superheroes. Maybe we'll get a commercial for the Mega Bloks sets, though I don't think they had a commercial for the non-movie sets.
As for TV spots, I'm not expecting them to be particularly good. I would like to see more of the cool apocalypse part or the underwater scenes in general but they will probably continue the heavy focus on the out of water scenes.
I'm sure Nick will do something special on air to promote the movie, like some special promos or a behind-the-scenes special like they did with the TMNT movie.